Who is participating in the study?
Two cohorts of individuals will be assessed (n=~1800 each), recruited from multiple sites. The first cohort, Multisite Clinical Center 1 (MCC1) will consist of individuals scheduled for total knee replacement (TKR). The second cohort, Multisite Clinical Center 2 (MCC2), will consist of individuals scheduled for thoracic surgery.
Multisite Clinical Center 1
Rush University and the Rush Institute for Translational Medicine partners, the University of Chicago and NorthShore University Health System will recruit patients undergoing total knee replacement surgery for the study.
Multisite Clinical Center 2
The University of Michigan and its partner institutions will recruit patients undergoing thoracic surgery for the study.